Nuffield Department of Clinical Medicine

The Nuffield Department of Medicine (NDM) is a large multi-disciplinary Department that links high quality basic biological science with medical application. Led by Professor Peter Ratcliffe FRS, who is both an active researcher in cell biology and an active clinician, the Department employs in the region of 1000 scientific research staff working in a range of basic science and clinical disciplines. Our researchers contribute to the teaching of 450 medical students within Oxford University's Clinical School. Our base at the Headington Hospitals campus, Oxford, is now one of the largest centres for biomedical research in Europe with over £200M invested in capital projects and research infrastructure over the last decade. The rapidly growing campus provides a vibrant, highly interactive environment for research development. We are particularly committed to the career development of young scientists, including those from basic science as well as clinical backgrounds. In 2006 the Oxford University / Oxford Radcliffe Hospital Trust partnership successfully competed to be one of five UK Biomedical Research Centres. We played a leading role in this initiative, which provides a range of new opportunities for basic scientists to interact with clinical medical research, and for career development of clinician scientists. In addition to its Oxford base, the Department operates a number of major overseas programmes in tropical medicine and global health, with research units in Thailand, Laos, Vietnam and Kenya supporting activities at numerous sites in S-E Asia and Sub-Saharan Africa. We also operate extensive epidemiological and clinical trials networks throughout China, India and South America. In Oxford, NDM maintains research platforms across structural biology, protein biochemistry, genetics, genomics, proteomics, cell biology, chemical and genetic screening, imaging, bioinformatics, medical statistics, epidemiology, and clinical trials. Thematic research includes cancer biology, immunology, vaccinology, infectious diseases, gastroenterology, dermatology, diabetes and metabolic medicine, renal medicine, respiratory medicine, stroke medicine, and geratology.

Series in this collection

All episodes

Title	Description	People	Date
Genetics and Diabetes	Dr Anna Gloyn talks about her research on the genetics of Diabetes.	Anna Gloyn	20 March, 2012
Infectious diseases in China	Dr Tao Dong tells us about her collaborations in China on infections such as HIV, flu and Hepatitis B.	Tao Dong	6 March, 2012
Infectious diseases in China	Dr Tao Dong tells us about her collaborations in China on infections such as HIV, flu and Hepatitis B.	Tao Dong	6 March, 2012
The treatment of severe malaria	Professor Arjen Dondorp tells us about his work on severe malaria and the development of new therapies.	Arjen Dondorp	21 February, 2012
The treatment of severe malaria	Prof. Arjen Dondorp tells us about his work on severe malaria and the development of new therapies.	Arjen Dondorp	21 February, 2012
HIV and children in Africa	Professor Sarah Rowland-Jones tells us about her work on HIV with children in Africa.	Sarah Rowland-Jones	7 February, 2012
HIV and children in Africa	Professor Sarah Rowland-Jones tells us about her work on HIV with children in Africa.	Sarah Rowland-Jones	7 February, 2012
Diabetes and Insulin Secretion	Professor Patrik Rorsman talks about diabetes and how beta cells within the pancreas control insulin secretion.	Patrik Rorsman	24 January, 2012
Diabetes and Insulin Secretion	Professor Patrik Rorsman talks about Diabetes and how beta cells within the pancreas control insulin secretion.	Patrik Rorsman	24 January, 2012
How can we live with HIV?	Dr Lucy Dorrell tells us how our immune system controls HIV and how we can live with this virus.	Lucy Dorrell	10 January, 2012
How can we live with HIV?	Dr Lucy Dorrell tells us how our immune system controls HIV and how we can live with this virus.	Lucy Dorrell	10 January, 2012
Yang Li	Yang Li joined Oxford in October 2010 after completing an undergraduate degree in Maths and Computer Science at McGill University in Montreal, Canada. He works on A comparative genomics approach to de novo genome assembly of next-generation sequencing.	Yang Li	13 December, 2011
Katherine Bull	Katherine Bull completed preclinical studies at Cambridge in 1999 and graduated in Clinical Medicine in 2002 at Oxford. She works on Whole Genome Sequencing in ENU mutagenesis and Autoimmunity under the supervision of Richard Cornall.	Katherine Bull	13 December, 2011
Zhe Zhao	Zhe Zhao joined Oxford in 2010, after completing an undergraduate degree in Biological Science at Tsinghua University in Beijing and a Msc at Leiden University Medical Centre. He works on Transcription Regulation in Coronary Development.	Zhe Zhao	13 December, 2011
Karolis Bauza	Karolis Bauza joined Oxford in 2009 after completing an undergraduate degree in Pre-Medicine at Belmont Abbey College, North Carolina. He works on Malaria pre-erythrocytic stage vaccines: targeting antigen combinations.	Karolis Bauza	13 December, 2011
Manuel Rivas	Manuel joined Oxford in 2010, after completing an undergraduate degree in Mathematics at MIT. He works on Rare and low-frequency DNA variants and their contribution to individual predisposition to common diseases.	Manuel Rivas	13 December, 2011
Viruses, how to be the perfect host	Professor Paul Klenerman talks about our relationship with persistent viruses, such as Hepatitis C.	Paul Klenerman	12 December, 2011
Viruses, how to be the perfect host	Professor Paul Klenerman talks about our relationship with persistent viruses, such as Hepatitis C.	Paul Klenerman	12 December, 2011
Genomics and Global Health	Professor Dominic Kwiatkowski talks about his work on global health, how genomics can help us fight infections such as malaria.	Dominic Kwiatkowski	24 November, 2011
Genomics and Global Health	Professor Dominic Kwiatkowski talks about his work on global health, how genomics can help us fight infections such as malaria.	Dominic Kwiatkowski	24 November, 2011
Annette Böhmer	Annette Böhmer joined Oxford in 2010 after completing an undergraduate degree in Medicine at the University of Leipzig. She is working on Defining Hepatitis C genotype 3 immune responses under the supervision of Dr Ellie Barnes.	Annette Böhmer	23 November, 2011
Specific Language Impairment	Dr Dianne Newbury talks about the contribution of genetics to specific language impairment.	Dianne Newbury	14 November, 2011
Specific Language Impairment	Dr Dianne Newbury talks about the contribution of genetics to specific language impairment.	Dianne Newbury	14 November, 2011
HIV immunology for Vaccine Design	Dr Seph Borrow tells us how her research on HIV Immunology helps design better vaccines.	Seph Borrow	1 November, 2011
HIV immunology for Vaccine Design	Dr Seph Borrow tells us how her research on HIV Immunology helps design better vaccines.	Seph Borrow	1 November, 2011
Renal Disease	Professor Chris Pugh tells us about the links between genetics, renal disease and oxygen sensing.	Chris Pugh	11 October, 2011
Renal Disease	Professor Chris Pugh tells us about the links between genetics, renal disease and oxygen sensing.	Chris Pugh	11 October, 2011
Dyslexia and Genetics	Dr Silvia Paracchini talks about the influence of Genetics in Dyslexia.	Silvia Paracchini	27 September, 2011
Dyslexia and Genetics	Dr Silvia Paracchini talks about the influence of genetics in dyslexia.	Silvia Paracchini	27 September, 2011
Aiming for a HIV vaccine	Professor Sir Andrew McMichael tells us about recent developments in the search for a vaccine against HIV.	Andrew McMichael	13 September, 2011
Aiming for a HIV vaccine	Professor Sir Andrew McMichael tells us about recent developments in the search for a vaccine against HIV.	Andrew McMichael	13 September, 2011
Palliative Care	Dr Bee Wee tells us about Palliative Care in Oxford and her research on end of life care and fatigue.	Bee Wee	30 August, 2011
Palliative Care	Dr Bee Wee tells us about Palliative Care in Oxford and her research on end of life care and fatigue.	Bee Wee	30 August, 2011
Tropical Medicine in Kenya	Professor Kevin Marsh tells us about his research on Tropical Medicine in Kenya.	Kevin Marsh	19 July, 2011
Tropical Medicine in Kenya	Professor Kevin Marsh tells us about his research on Tropical Medicine in Kenya.	Kevin Marsh	19 July, 2011
Cancer and Protein Crystallography	Professor Yvonne Jones talks about cell-cell communication and how this can help us develop new drugs.	Yvonne Jones	6 July, 2011
Cancer and Protein Crystallography	Professor Yvonne Jones talks about cell-cell communication and how this can help us develop new drugs.	Yvonne Jones	6 July, 2011
Obesity and Diabetes	Professor Fredrik Karpe explores the links between obesity and diabetes.	Fredrik Karpe	21 June, 2011
Obesity and Diabetes	Professor Fredrik Karpe explores the links between obesity and diabetes.	Fredrik Karpe	21 June, 2011
Proteomics and Biomarkers	Dr Benedikt Kessler tells us how proteomics helps find biomarkers.	Benedikt Kessler	7 June, 2011
Proteomics and Biomarkers	Dr Benedikt Kessler tells us how proteomics helps find biomarkers.	Benedikt Kessler	7 June, 2011
Role of Lifestyle and Diet in Cancer	Professor Tim Key tells us about the role of life style and diet in the development of cancer.	Tim Key	10 May, 2011
Role of Lifestyle and Diet in Cancer	Professor Tim Key tells us about the role of life style and diet in the development of cancer.	Tim Key	10 May, 2011
Autophagy	Dr Katja Simon tells us about her research on autophagy in red blood cells.	Katja Simon	26 April, 2011
Autophagy	Dr Katja Simon tells us about her research on autophagy in red blood cells.	Katja Simon	26 April, 2011
Spondyloarthritis	Professor Paul Bowness tells us about his work on spondyloarthritis.	Paul Bowness	12 April, 2011
Spondyloarthritis	Dr Paul Bowness tells us about his work on spondyloarthritis.	Paul Bowness	12 April, 2011
Obesity and Genetics	Dr Cecilia Lindgren explores the links between obesity and genetics.	Cecilia Lindgren	29 March, 2011
Obesity and Genetics	Dr Cecilia Lindgren explores the links between obesity and genetics.	Cecilia Lindgren	29 March, 2011
Iron Metabolism	Dr Hal Drakesmith tells us how his work on iron availability can help us fight infections.	Hal Drakesmith	15 March, 2011
Iron Metabolism	Dr Hal Drakesmith tells us how his work on iron availability can help us fight infections.	Hal Drakesmith	15 March, 2011
Tuberculosis	Professor Helen McShane talks about her work on a new vaccine against tuberculosis.	Helen McShane	1 March, 2011
Tuberculosis	Dr Helen McShane has been working on a new TB vaccine for 10 years. She explains why developing countries are especially in need of a new vaccine since HIV and TB epidemics overlap and show a devastating synergy.	Helen McShane	1 March, 2011
Drug Discovery	Professor Chas Bountra explains how new drugs can offer novel treatments for neurodegenerative and gastrointestinal diseases, as well as pain disorders.	Chas Bountra	20 December, 2010
Drug Discovery	Professor Chas Bountra explains how new drugs can offer novel treatments for neurodegenerative and gastrointestinal diseases, as well as pain disorders.	Chas Bountra	20 December, 2010
Genetic Variation in Inflammation and Immunity	Dr Julian Knight explains how genetic variants modulate gene expression and influence the susceptibility to commom diseases.	Julian Knight	29 November, 2010
Genetic Variation in Inflammation and Immunity	Dr Julian Knight explains how new insights into genetic variants which modulate gene expression allow us to better understand why people develop these diseases, and allow us to target treatments more effectively.	Julian Knight	29 November, 2010
Chromatin Remodelling	Dr Erika Mancini explains the role of chromatin in the regulation of gene transcription.	Erika Mancini	15 November, 2010
Chromatin Remodelling	Dr Erika Mancini explains how malfunctions in the regulation of chromatin structure often leads to complex multi-system diseases and cancer, notably leukemia.	Erika Mancini	15 November, 2010
Malaria and Global Health	Dr Climent Casals-Pascual explains how the development of new tools to diagnose and manage malaria more effectively will allow us to decrease the mortality of this condition.	Climent Casals-Pascual	2 November, 2010
Malaria and Global Health	Dr Climent Casals-Pascual tells us how new tools can help us diagnose and manage malaria more effectively.	Climent Casals-Pascual	2 November, 2010
Malaria Vaccines	Professor Adrian Hill talks about recent developments of vaccines against malaria.	Adrian Hill	18 October, 2010
Malaria Vaccines	Professor Adrian Hill has been studying the immune system and malaria susceptibility in African children for years. We asked him about his latest findings in the development of vaccines against malaria.	Adrian Hill	18 October, 2010
Women's Health	Dr Krina Zondervan is interested is women's health conditions, particularly endometriosis. Dr Zondervan studies genetic, molecular and environmental factors influencing this complex disorder.	Krina Zondervan	30 September, 2010
Women's Health	Dr Krina Zondervan talks about endometriosis, an incapacitating women's health condition.	Krina Zondervan	30 September, 2010

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