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Epigenetic modifications and cancer

Series
Cancer
Video Embed
Professor Skirmantas Kriaucionis aims to to elucidate the molecular function of DNA modifications in normal cells and cancer.
Although all cells in our body have the same genome, they look different and perform different functions. Epigenetic modifications such as methylations ensure which sets of genes are expressed in specific cells and how this specificity is inherited. Cancer cells show particular epigenetic abnormalities which can be targeted for cancer therapies.

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Targeting epigenetics to treat cancer

Transcription is a tightly regulated process, where chemical modifications initiate the duplication of genetic material. This epigenetic process is often dysregulated in cancer, but it can be targeted with small molecule inhibitors.
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Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Cancer
People
Skirmantas Kriaucionis
Keywords
cancer
Epigenetics
DNA
molecules
cells
genome
Department: Nuffield Department of Clinical Medicine
Date Added: 14/12/2016
Duration: 00:05:44

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